Victory over Manchester United has City clear at the summit with three games to play.
Guardiola said: "We have to be so calm because on Saturday we go to Burnley and we know how difficult it is. We have been playing like this in the last six months and we have not had a break. The players are incredible.
"We do not read the papers or switch on the TV. The players have a lot of massages and they have to eat and sleep well. We need everybody together at this stage."