Spurs land on Merseyside on the back of a poor start to the season with Liverpool still unbeaten under their new boss across all competitions so far in 2026/27.
Alisson Becker has been unmoved as first choice in goal, but Iraola will offer deputy keeper Giorgi Mamardashvili a chance to impress n this game, after also hinting he tried to sign the Georgian during his time in charge of Bournemouth.
"There are few doubts with Alisson, he's playing very well. I rate Giorgi very highly, I know him from Spain.
"We tried to sign him for Bournemouth before I came here. For me, he's a very good keeper and he's going to start tomorrow."
Iraola also confirmed Joe Gomez is back in full training and could be included in the matchday squad, but Conor Bradley is still a few weeks away from a return.
Rio Ngumoha is also expected to be handed a start with fringe names including Lewis Koumas and Jayden Danns also in the reckoning as part of a refreshed starting XI at Anfield.