The Reds have only suffered defeat in one of their last 10 top-flight home games as they welcome the Eagles to Anfield on Saturday afternoon.
Palace will be preparing for their Conference League semi-final with Shakhtar Donetsk just 5 days after the clash with Liverpool which is good news for Slot who need just a few more wins to secure Champions League football for next season.
However, Palace have also gone four unbeaten in the Premier League since March's narrow defeat to Manchester United and won’t hold back against a Liverpool side who are in fine form.
Slot will be without the likes of Conor Bradley (Knee Injury), Giovanni Leoni (Knee Injury) Giovanni Leoni (Knee Injury), Giorgi Mamardashvili (Knee Injury), Alisson Becker (Other) in defence.
Third choice goalkeeper Freddie Woodman is set to start for the Premier League champions as Slot called for fans to back the shot stopper who fared well against Everton last week.
"I think for a reason we have signed an experienced third goalkeeper," said Slot. He is ready for it, but it will always be helpful if the fans are there to support him tomorrow."
Finally, Hugo Ekitike (Calf/Shin/Heel Injury) is also out and will miss the rest of the season after rupturing his Achilles against Paris Saint-Germain earlier this month. Slot will turn to Alexander Isak to lead the line, a player who is yet to find his feet in Merseyside.