City, sitting second from top, face second from bottom Forest on Saturday afternoon as Enzo Maresca hopes to grab three points in an effort to close the three-point gap on champions Arsenal.
Forest have managed just one league victory in nine matches and are winless in their last six home league games as they come up against a ruthless City side.
However, Forest have taken points from two of their last three home league meetings with City, a stat which may worry Maresca and his side heading into the clash.
Man City vs Nottingham Forest team news
Forest are missing Nicolas Dominguez (muscle) Igor Jesus (calf), while defender Nicolo Savona (knee) remains absent.
City are only without Antoine Semenyo (knee) as they enter the game with an almost fully fit side.
Man City vs Nottingham Forest predicted line-ups
Nottingham Forest: Sels, Cunha, Milenkovic, Murillo, Aina, McAtee, Schlager, Williams, Ndoye, Gibbs-White, Delap.
Manchester City: Donnarumma, Nunes, Khusanov, Dias, Gvardiol, Anderson, Bouaddi, Ndiaye, Fernandez, Doku, Haaland.
Man City vs Nottingham Forest kick-off time
City and Forest clash at the City ground for a 17:30 kick-off, UK time.
Form
Man City: WLDLW
Forest: LDLLL
Key stats
City have lost consecutive Premier League matches against Aston Villa and Brighton but secured a narrow win against RB Leipzig in the Champions League in midweek.
Forest have collected just one point at the City Ground this season and are yet to score there in the league.
With nine points collected from a possible 12 away from home, City are the favourites for this game.