The 3-1 win saw Liverpool replace Aston Villa in fourth place on the Premier League table. Alexander Isak and Andrew Robertson had Liverpool 2-0 ahead before Daniel Munoz pulled a goal back for Palace. Florian Wirtz eventually restored the two goal for Liverpool late on.
Slot said afterwards: "As one that we haven't had yet and that's almost impossible because all the things we've experienced this season... you could write a book about it, as I said earlier. Every time I think now, OK, now there's nothing that can happen anymore that didn't happen yet.
"But we saw it today - a goalkeeper on the floor and then conceding a goal. The end result is, of course, positive that we were able (to win) in a game where we conceded a goal that you prefer not to concede - you never prefer to concede a goal - but not in this way.
"But we kept on fighting until the end and even scored for 3-1. So, bad luck we've had many times this season, usually it ends up in us dropping points but not today. That's a very positive thing. If you just look at the performance of both teams, I think Palace deserved to come back into the game because they were playing a good game, they were close to scoring goals, the margins were really small, but another injury (to Mohamed Salah) of course after a win, that sums up again our season."
On Isak's first Premier League goal for Liverpool, Slot added: "It's really nice that he scored one because when we signed him we knew he could score goals and that's what he showed today.
"Many times this season we've had better chances than we had today, that's why it's also important to have players that can score also goals like this, because that can give you a big lift in a game."