Ferguson is leaving the £2.16m-a-year job after a face-to-face meeting with United's co-owner.
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Taking to social media, Cantona blasted: “Sir Alex Ferguson should be able to do anything he wants at the club until the day he dies. Such a lack of respect. It’s totally scandalous. Sir Alex Ferguson will be my boss forever!
"And I throw them all in a big bag of s***!”
Former United defender Rio Ferdinand also reacted, posting: “If Sir Alex can be taken out, then NO ONE IS SAFE at Man Utd – anyone can get it now. Ineos sending a message to ANYONE at the club?!?”
It's also emerged Ratcliffe plans to axe the annual Christmas party for club staff.