The Cameroon forward joins United from Brentford for a fee rising to £71m.
Upon Mbeumo putting pen to paper, Wilcox said: “Bryan’s goals and assists record in the Premier League is exceptional, his remarkable consistency has put him amongst the most productive players in England for the last three seasons.
“Bryan’s belief in our project and determination to join the club confirmed that he was the perfect fit for Manchester United and the culture that we are developing.
“We are delighted to have secured another one of our primary targets ahead of the pre-season tour. The experience in the US will be the perfect opportunity for Bryan to work with Ruben and his new team-mates as we prepare for an exciting season ahead.”
Meanwhile, Mbeumo said: "Everybody told me about the environment that is being created here and how exciting the plans are for the future. This is a massive club, with an incredible stadium and amazing fans, we are all really determined to challenge for the biggest trophies.”