Following a big-money switch from Bayer Leverkusen last summer, Wirtz has had the world on his shoulders throughout the season as many supporters expect him to live up to his £116M price tag.
The 22-year-old struggled at the start of the campaign but has grown into his role under now manager Arne Slot who knows how to get the best out of the German international.
Now, with the World Cup less than 50 days away, Klopp has spoken on Wirtz who he believes will enjoy the tournament across the US, Canada and Mexico.
"I hope Flo Wirtz will have a fantastic, fantastic World Cup. I think he has everything you need to be a standout player.
"I don't want to put any pressure on the boy. I really think he showed already how good he can be in a difficult season.
"I wish Virgil (van Dijk) will have a great tournament. I really wish for Mo (Salah) that he will have a great tournament. I honestly wish that Sadio (Mane) will have a great tournament. Macca (Alexis Mac Allister), if he won, if they win it again. It was so nice to see him with a medal around his neck when he came back to Brighton.
"So many (of my) former players are part of the World Cup, which is really, really nice. And to see how time flies."
Klopp is now head of global football at Red Bull, and will work at the World Cup for German television as a pundit where he can watch Wirtz from the sidelines alongside some of his other former players who will be delighted to see him on the sidelines.
