Jackson is in United's traveling squad due to injury concerns, reports the Manchester Evening News' Samuel Luckhurst.
The 18 year-old defender has made 15 appearances for the U18s and has played a further six games for the U21s in Premier League 2.
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Harry Maguire is United's only fit senior centre-half, with Willy Kambwala not traveling to London for the clash with Coventry City.
Midfielders Mason Mount and Sofyan Amrabat are also unavailable.