Pocognoli's men were unable to find the breakthrough in a goalless stalemate against Slovenia, and the Tartan Army will be expectant in their first home game since their disappointing showing at the FIFA World Cup this summer.
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Switzerland will arrive full of confidence after cruising to a 3-0 victory in North Macedonia.
Scotland predicted lineup v Switzerland:
Scotland XI: Gunn; Welsh, McKenna, Hendry; Robertson, Ferguson, Gilmour, Hickey; McGinn; McBurnie, Bowie.
Scotland v Switzerland kick off time
Kick off at Hampden Park is set for 7:45pm.
Key stat
This will be just the third head-to-head meeting this century, with Switzerland losing just one of the last six meetings (W2, D3). Scotland picked up their sole point of Euro 2024 with a 1-1 draw against the Swiss in the most recent meeting.