Premier League champions Liverpool will meet FA Cup winners Crystal Palace.
Slot told Liverpool's website: "As someone who has followed English football all my life, I know how special a game at Wembley is.
"I had my first taste of this place as a head coach last season, and I am really looking forward to being back out there with my team.
"For us, this is the ideal game to complete our preparations for the new season. As a head coach, you want three things at this time of year: to get some good work in on the training ground, competitive and challenging games and to steer clear of injuries.
"We know, of course, what we achieved last season, and it is important from our point of view that we maintain the standards we set during the past 12 months."
On Palace, Slot also said: "They are a team which always makes it difficult.
"They have good players, a very good coach with a clear idea of how to play, and to achieve what they achieved last season, winning the Emirates FA Cup here against Manchester City, was really impressive. They deserve a lot of credit for that."