The 22-year-old has been sensational for Barcelona this season, scoring 12 goals and providing 16 assists in his 39 games across all competitions.
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Lopez was subject to interest from Chelsea last summer but had no intention of leaving his boyhood club for the Premier League side.
According to El Chiringuito TV, Man United are now going to test his resolve and are willing to pay €100 million to bring Lopez to Old Trafford.
A deal is increasingly unlikely, however, with Barcelona and manager Hansi Flick uninterested in selling the attacking midfielder.