Rashford was an energetic figure for most of the game, albeit with little end product.
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He had to come off in the 60th minute, with Brazilian Antony taking his place in the team.
Asked post-game by MUTV about Rashford's injury, manager Erik ten Hag stated: "I'm not sure, but I don't think it will be long term."
United next take on Bournemouth in the Premier League away from home on Saturday.