Guardiola was asked about Nottingham Forest's complaints this week.
He said: "Absolutely disagree. There are always in every league, this will happen more and more but of course I never had doubts about that.
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"The referees want to do the job as best as possible. They feel the pressure, we put pressure on them for the passion of the game for the moment, but when I sit here and reflect they try to do their best and are under scrutiny with the cameras there.
"They make a mistake, they feel bad. It's normal. When they do the job, they want to do it well. The game is so difficult, it is fast and quick, decisions have to be made in one instant. It's not easy."