The 26-year-old has found minutes hard to come by under new manager Cristian Chivu, starting just one Serie A game so far this season.
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Tuttomercatoweb reports that the Italy international’s path is being blocked by Petar Sucic and Piotr Zielinski, and a January exit is ‘very likely’.
According to a report from Sport Witness, Newcastle were interested in signing Frattesi in the summer, but he ended up staying at Inter.
It’s understood that Eddie Howe’s side will reignite their interest in January, with the Serie A giants more willing to sell the midfielder.