United won 2-1 with Fernandes and Casemiro on the scoresheet. Chelsea keeper Robert Sanchez and Casemiro both saw red before halftime.
Fernandes said at the final whistle: "You want to perform but at the end of the day what matters is points. We haven't been getting the points we wanted.
"At the end of the game we were very strong in defending our box and putting them in positions of crossing.
"We got the (Chelsea's) red card because our mentality was starting the game so strong. The players have to run behind whenever Ben (Sesko) goes for the ball and that's what Bryan (Mbeumo) did.
"It (United's red) didn't change anything. We wanted to close the middle. Without (Liam) Delap who makes the runs for the team, Joao Pedro wants to link up.
"We gave them the chance to go down the side and then close them with our wing-backs. Our centre-backs were very good to defend the box."
On 100 United goals and 200 Premier League appearances: "Obviously I'm very proud of that - two massive milestones. Not something I was aiming for. I just aimed to play the next game."