Slot has gone with the same XI that defeated Real Madrid in their midweek Champions League tie.
The Reds have options to bring on in attack as Alexander Isak is on the bench, alongside Cody Gakpo and Federico Chiesa.
Meanwhile, Manchester City boss Pep Guardiola has brought Rayan Cherki into his starting XI and also has welcomed back defender Ruben Dias and skipper Bernardo Silva.
Tijjani Reijnders, John Stones and Savinho have dropped to the bench after starting in the Champions League win against Borussia Dortmund.
Manchester City XI: Donnarumma, Nunes, Dias, Gvardiol, O'Reilly, Gonzalez, Silva, Foden, Cherki, Doku, Haaland.
Subs: Trafford, Reijnders, Stones, Ake, Marmoush, Ait-Nouri, Savinho, Bobb, Lewis
Liverpool XI: Marmadashvili, Bradley, Konate, Van Dijk, Robertson, Gravenberch, Szoboszlai, Mac Allister, Salah, Wirtz, Ekitike.
Subs: Woodman, Gomez, Endo, Kerkez, Isak, Chiesa, Jones, Gakpo, Ngumoha.