The Red Devils are aiming to complete the top-flight double over the Blues for just the second time after the 2019-20 season as Carrick and his side chase down Champions League football.
United suffered a home defeat last time out, losing 1-2 against rivals Leeds United whilst Chelsea have now won just one of their previous seven Premier League outings, losing four of their past five.
Both sides are aiming to bounce back this weekend in a clash that will be hugely important for the race for European football.
Martinez and Maguire suspensions
Speaking first on Lisandro Martinez who was sent off in the defeat to Leeds for pulling Dominic Calvert-Lewin's hair, Carrick says the club must move on and focus on the game ahead.
“No (he is not available). We didn't agree with it, it's obvious how I felt after the game, and I still feel that way now. I don't want to go into it now, it is what it is. We have to accept it and move on.”
On Maguire also being banned for the clash following his language towards match officials: "To be honest, there's not much to react to. I'm disappointed, of course. We've had a few reasons to be disappointed over the last few weeks. We have to move on because the decision has been made."
Heaven to start?
Ayden Heaven will step into defence to cover for Maguire and Martinez as he partners with Leny Yoro at the back. Carrick says Heaven is in a good place as he implies he will start.
“Ayden is in a good place. He's still young, and he's progressing through the early stages of his career, so I think it's natural for him to play some games and not some others. He's training really well, improving and listening.
“It's natural for a centre-back of his age, and he's ahead of schedule in terms of the games he's played. He trained with England a few weeks ago and did well. He's looking forward to the game, for sure.”
United must be confident against Chelsea
Finally, Carrick was asked about the challenge of facing Chelsea who are unbeaten in each of their previous five Premier League meetings with United at Stamford Bridge, winning each of the last two.
"It's an important game, we're in a good position but we need to keep building on that. It's a tough place to go and we always have tough games down there. Most of the time they have been good games in terms of the product, so we'll be ready for that and we take the confidence from what we've built.
"We didn't get the result against Leeds, but certainly, the way we finished the game and the character we showed, we need to take that into this game."