Tension between the two clubs are at breaking point as Liverpool attempt to prise Alexander Isak away from Newcastle before next week's transfer deadline.
Asked if the situation will further raise the temperature at St James' Park tonight, Slot said: “If that is even possible.
“Because it was very intense the last time we played there as well. It's actually always that way when Newcastle play a home game, let alone an evening game.
“It's always so, so, so intense. So I don't know if that is an extra reason for them. I don't even know if it is what the players and the manager are thinking as well.
“Of course, social media and people write a lot, but is this truly what the players are thinking and the manager is thinking? I don't know. I have no clue.”