Xavi, who played for Guardiola at Barca, was sacked on Friday.
Guardiola said: "What can I say? It's never good news because it means that something didn't work.
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"A manager sacked by the club. I don't know the reasons for what happened. We spoke today at breakfast of so many technician dismissals. Normally managers move a lot.
"In our job you have to win otherwise you are in a dangerous position, whether you are young or old, you have to win, do a good job and be good at many things otherwise this happens."