Midfielders Rio Kyerematen and Leo Black are called up for the first time. But 16 year-old Premier League debutant Mikey Moore is not included due to England U17 commitments.
Captain Heung-min Son will be on the plane for Australia.
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Tottenham travelling squad:
George Abbott
Brandon Austin
Rodrigo Bentancur
Leo Black
Alfie Devine
Jamie Donley
Radu Dragusin
Bryan Gil
Tyrese Hall
Brennan Johnson
Dejan Kulusevski
Rio Kyerematen
Emerson Royal
James Maddison
Ashley Phillips
Pedro Porro
Yago Santiago
Pape Matar Sarr
Dane Scarlett
Oliver Skipp
Heung-Min Son
Micky van de Ven
Guglielmo Vicario
Alfie Whiteman