United won 2-0 on the day, with both goals coming after Romero was sent off on 29 minutes for a heavy challenge on Casemiro.
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"No, there's not (any regrets about making him captain),” Frank said in his post-match press conference.
“And also, he was sorry for the incident, he apologised to his team-mates in the changing room. No, I think he's one of the most important players, and I think when he performs top, he's driving the team.”
Asked if Romero had let him down, Frank said: “We haven’t spoken specifically about this situation because he apologised to the players, to us, to the team in there.
"That’s enough for me for now. And then, how can you say, that’s it. Nothing more to do for now.”