In arguably the most important game for England since the World Cup final in 1966, Tuchel’s side faced off against Lionel Messi’s Argentina.
England took the lead through Anthony Gordon in the 55th minute, but after several defensive substitutions, they gave up the impetus to Argentina.
Enzo Fernandez scored from long-range to make it 1-1 and just seven minutes later Lautaro Martinez secured a comeback win for Argentina.
Speaking to reporters after the game, Tuchel gave a stanch defence of his decision.
"We were close but couldn't keep the level up after we scored."
When Asked about his subs, he said: "Yeah I did also offensive substitutions in the last games. We tried to help the players.
“We conceded straight away. We decided to go to a back five because the gaps were far too open, they won every header and kept crossing and crossing.
"We went to a back five to close the gaps inside and be strong in the air because straight after our goal, with no substitutions, we conceded way too many crosses and way too many chances.
“We tried to help but of course the responsibility is on the coach. If it doesn't go well, it's easy to say it was wrong.”
"It doesn't help if you don't have the ball. We couldn't get out. We wanted to go for the second goal but I had not the feeling that offensive substitutions would help.
“We stayed in our 4-4-2 but became more and more passive, we couldn't win any balls or keep the ball. It was not a structural problem.
“We changed nothing after the goal, but the match changed completely.
"But it's no problem, I can understand these discussions. You can discuss this with a million coaches.
“I have to make a decision on the pitch. I take the responsibility. No regrets in the moment. The team gave everything and we were very, very close.
"We deserved to be 1-0 up, we played one of our better matches, maybe the best match in the circumstances.
“The team was top. We couldn't bring it over the line. No, in the moment, no regrets."