Wolves goalkeeper Rui Patricio hopes to use his know-how in their Europa League push.
Yet in goalkeeper Patricio and Joao Moutinho they have players who have upset the odds before in big one-off tournaments, playing for Portugal in the final of Euro 2016 when they beat hosts France 1-0.
"What we've done so far over two legs and what we are going into now is completely different," says Patricio.
"We have to adapt to a new reality, in a neutral venue and without fans. They are matches where you need to perform to a maximum level. I mean there is no second game to make up for a poor performance in the first.
"This is knock-out football and we have to be at our best as it's the only chance we have.
"We have some experienced players, not only me but Moutinho, Ruben (Neves). Of course we try to pass it on because the way we prepare is the most important thing. It is logical the younger players see the way we prepare and, without a doubt, we are an example for them."