Lloris suffered a dislocated elbow in defeat at Brighton that will not require surgery but will mean he's ruled out until next year.
“It's always the same answer, I'm ready," Gazzaniga told the club's website. “I try to be focussed. I believe in myself and my team-mates, and that's the only way. We know we have to be strong. At home, especially, we have to be strong.
“I wasn't comfortable seeing Hugo coming out of the game in that way. Everyone knows what he means for the team and for the Club, our captain.
“Now it's about having the right mentality and being focussed, starting against Watford."