It was suggested to Huddlestone that his was a must-win game with Inter in the same group.
"It's only the second game of six in the group, so I don't think it is must-win at the moment," the midfielder told the Spurs website.
"Before the tournament we'd look to try and win all three home matches.
"If you then manage to nick a couple of away points you'll more than likely qualify. But we go into every game looking to win and this is no different.
"We won't change our approach to the game, especially at home. We know how we like to play and that's attacking, getting the ball wide and letting our wingers cause problems. Everyone drew in the first round of matches and we'll be going to try and win the game.
"Werder Bremen have been in the Champions League for a number of years but we went there and put on a good display. So I don't think we need to be fearful of anyone in the group. We'll go out there and look to enjoy our football and that when we're at our best."