Gouffran was carried off following an innocuous challenge with Kyle Walker.
The France international received oxygen on the pitch as he was treated and manager Pardew is hoping his January recruit has not suffered a break.
"He's had an impact on his shin which was a nasty gash, he'd have probably come off with a gash anyway but it's whether there's any bone damage. He's gone for an x-ray and we cross our fingers that comes back okay," he said.
"I haven't seen it back. I think when you see a big gash it disturbs you as a player. The doctor was 50-50 from his experience of looking at it (as to whether or not it was a break)."