Manchester United captain Nemanja Vidic says they can hurt Arsenal's title bid with victory tonight.
Although Vidic knows nothing is won in December, posting three points against their title rivals will strike a huge blow.
The centre back said: "It is the biggest game so far this season. Arsenal are playing good football at the moment, they are top of the league
"It would be nice if we could win the game and take the lead. It is still early to speak about advantages, but it would be nice."