The Cottagers have a miserable record against their west London neighbours, winning just one of 23 Premier League clashes, but could be playing them at a good time given the Blues' hectic fixture schedule.
"I am not sure," Jol said about the timing. "Sometimes you have the rhythm, which gives you the advantage.
"We played on Saturday, we will play again Wednesday and then against Arsenal.
"It is about legs so it depends on who is playing. If they play the same team, that probably could help us.
"If not, they are big enough as a squad to play four or five different players and I think they probably will."