Spurs will now face the Bundesliga club in the second leg at White Hart Lane on Thursday and Pochettino will have to field a strong XI in order to overturn the deficit.
"Sometimes we rotate, sometimes maybe I made a mistake," he said.
"We analyse our decision a lot. We can always do better and for that we are open to learn.
"Sometimes it is difficult and I accept in a very good way the criticism because always in football if you win you are a genius, if not, you are a disaster.
"For me it is important to keep all players motivated. It is very important for our supporters that they know I believe in all the players in our squad."