Spurs star striker Kane refused to rule out an exit from the club when speaking on Sunday, while Borussia Dortmund chief Hans-Joachim Watzke has admitted Sancho could leave.
And Ferdinand thinks the pair are just the players United need for a title push.
He told The Sun: Ferdinand said: "Harry has always been coy and held back but he's dropped a couple of bombs. He's been waiting for the dream at Spurs to materialise but it hasn't happened. He's frustrated.
"Do you think Harry would be happy, fulfilled and satisfied if he scores goals, break records but with no trophies at the end of his career? No. He will be upset and devastated.
"I think that statement means Harry is off, he wants to win trophies and that will alert clubs.
"He will go for massive dough, at least £130m in today's market."
On Sancho, he added: "I want Jadon to go to a team where he will play, improve and get trophies. He's been linked with United, Chelsea, PSG but I think United is the place for him to go because I'm biased.
"(Marcus) Rashford, (Anthony) Martial, Kane, Sancho, that would intimate a lot of centre-halves before a whistle is blown. Definitely."