Manchester United will be without Phil Jones and Eric Bailly for their Champions League clash with Basel on Tuesday due to suspensions.
The duo of Chris Smalling and Victor Lindelof is likely to step in front of keeper David de Gea.
Neither of them has made a league appearance this season, but the Spaniard insists that he is comfortable playing with all of United's defenders.
"I feel really well with all of my defenders," De Gea said.
"If someone cannot play or it's the decision of the manager, I feel good with anyone."