Mohamed Salah has been linked with Real this summer, but Del Bosque insists the Egyptian would struggle to get off the bench.
He told Radio Cope: "Real Madrid is the best team in Europe.
"I cannot find a Liverpool player that could replace one of Madrid. Bale, Benzema, Cristiano, Asensio and Lucas Vázquez are better than Salah, or just as good."
Asked for prediction, Del Bosque was clear: "4-1."