Tuchel was asked about Conte previously saying there was a big gap between his side and Chelsea.
He said: "I never felt a huge gap in preparing these matches, they are always close matches and they have a very talented squad.
"I know what we invested and to what level we played to beat them four times against this quality of team. For everybody, this game means so much.
"I admire Antonio Conte but I don't always believe everything he says entirely. They had something very clear last season to fight for, and they reached Champions League football.
"They took advantage of the situation and had a very aggressive transfer period and an excellent period to strengthen their squad in quality and depth. That is what we are facing."