Atalanta coach Gian Piero Gasperini recognises it's a big weekend for Charles de Ketelaere.
Gasperini said: "He played a decent game on Monday, he is a boy who is giving good answers.
"His growth is constant, being an ex he will have very high motivations.
"We are playing an important match at home, we must hold on to the pitch factor to bring out maximum energy, as Milan did.
"This is football, we have to make the changes."