Mings partnered £12 million summer signing Ezri Konsa in defence after first-choice centre-back Bjorn Engels was ruled out through injury.
Konsa made his debut, with goalkeeper Jed Steer also drafted in for his first Premier League start of the season after injuries to Tom Heaton and Jack Grealish handed manager Dean Smith a major injury headache ahead of kick-off.
And Mings has posted his reaction on social media.
"Not good enough today," he posted on Twitter.
"Thank you for your support. Congrats @ekonsa_ on your full PL debut."