Under Amour launched the 'Power in Pink' campaign in 2003 and this year 30 high-profile athletes will wear the unique boots.
Xhaka, playing for Switzerland against Hungary and Portugal this weekend, will also lace up the boots when playing for Arsenal.
The 25-year-old posted a touching tribute on Instagram: "Breast cancer is a horrible disease that affects entire families. Not just women - but children, husbands, mothers and fathers back home.
"It takes enormous strength and courage to go to battle with such an enemy every day of your life without losing hope.
"I'll therefore proudly wear their fighting spirit on my boots."
Granit Xhaka will wear pink boots in his next game to support breast cancer awareness pic.twitter.com/Dbo7cmqH36
— UberArsenal™ (@UberAFC) October 5, 2017
The money from the campaign will be donated to six cancer centres as well as help 50 people suffering from the disease.