He is suffering the same niggle on his right foot that he had on his left for most of last season.
Wenger appears convinced that Arsenal have identified the rare problem early this time, so Vermaelen will return soon.
He said: "There's no medical reason why he should not play 50 games on the trot now.
"I always was a bit suspicious — why should that happen only on one side?
"I thought at some stage that the other side will come as well and it did."