Qualification would bring with it some 8.6 million euros (£7million) in prize money, with each subsequent group home match worth around £3m of additional match-day revenue.
Wenger knows all too well what is on the line against Slaven Bilic's side, who defeated Feyenoord 5-2 on aggregate in the third round of qualifying when former Chelsea striker Demba Ba scored a hat-trick in the second leg.
"We are desperate to do it because we want to play in the Champions League and we know how big these games are," said Wenger.
"We are desperate to go through. No matter what it costs we want to go through.
For the big stories and the banter follow us on Twitter: @tribalfootball