Villa take on the second-placed City at Etihad Stadium tomorrow and the Scottish tactician is aware that Tevez may not come back into first team contention after refusing to play in the Champions League recently.
But McLeish says that the City players will not be thinking about the Argentine and knows that there is plenty of depth in Roberto Mancini's squad to do some damage.
"I don't think the Tevez situation will affect the mindset of the City players," he said. "I don't think it would bother the players too much.
"They get on with it because I know in my time as a player that, when managers and players left, the media would say 'it's the end of the world'.
"After about a week or two, after reading all the hype, then you just get on with it. As a player you are only really looking after yourself and making sure you are ready and prepared for any game coming up.
"I wouldn't expect Tevez to be in the squad but I'm not going to lose any sleep over it because we know they've got fantastic replacements," McLeish added.
"We know whatever side City put out that they have a very strong team and on paper they should be too strong for most teams in the Premier League."