Southampton boss Mauricio Pellegrino admits Virgil van Dijk has told the club he wants to leave.
Pellegrino revealed the Dutch defender, a target for Liverpool earlier this summer, has been ordered to train separately from the rest of the squad.
"He is not involved with the team because psychologically he is not 100 per cent," Pellegrino told BBC Radio Solent.
"When I was talking with him, the boy said that he is not available to play because he wants to leave.
"I need to work with a player that works at 100 per cent to defend Southampton.
"This is the decision. I had to say, 'Okay, if you don't want to be involved because you don't feel okay, you have to train alone until this period of time'."