Negredo, 27, says he is happy in Spain but admits his ambitions are not really being met and has not ruled out a switch.
He said: "Right now, I'm at Seville and like it very much.
"If I stay that'll be fine but if I leave then it will be because it benefits both the club and myself.
"I'm happy on a personal level - but collectively we have not achieved the goals we wanted. Now perhaps I am at a decisive moment for my future."