The association, also known as the Great 4 (G4) was launched at a media briefing on Tuesday by the respective club fans chairpersons Aldrine Nsubuga (Liverpool), Allan Ssekamatte (Chelsea), Denis Mbide (Arsenal) and Mark Namanya (Manchester United).
Aldrine Nsubuga, the secretary of the new body, elaborated on the foundations of the G4.
"Through the various activities by these clubs' associations, we as Premiership club chairmen found the need to unify the growing number of Barclays Premiership fans under an appropriate structure to deal with the growth," he added.
To confirm the authenticity of the association, vice chairman Namanya explained its aspirations.
"We want to use this forum to encourage all the fans nationally to support local football. There's need for people to redirect the Premiership passion to our local football and this we shall achieve through various activities," he said.
"This is not just about gathering to watch games, party and then go away. We shall also take part in community development activities across the country.
We simply can't switch off from our problems like diseases and poverty. Such issues will be addressed," added Mbide.
"The association will also endeavour to create a structured connection between the local fans and the Premiership stars who will visit Uganda as goodwill ambassadors," revealed Ssekamatte.