N'Zogbia, former United flier and constant thorn in the side of his old club in previous meetings, will be pitched into direct competition with the former Manchester United man.
"It'll be interesting," Simpson told The Journal. "I played against him in the Wigan away game last season, he's one of those players where you can't afford to switch off for a second.
"I wasn't here when he was at Newcastle, but I know what he's all about. You've got to look forward to playing against good players. Hopefully, we can build on this match, go into that game and keep another clean sheet."