De Laurentiis feels fatigue is affecting his players.
"I was worried from the very start this evening, as the team was visibly tired and we lost Christian Maggio after 25 minutes.
"Juventus have the determination of a team fighting to the end for the Scudetto, plus they are compact and efficient in midfield and not tired from Champions League efforts.
"We've got to scrape what remaining energy we have and rediscover the sharpness that all the teams who competed in Europe are struggling with now. We have strength in depth and not just a first choice XI, so we should give room to those who haven't played as much, are younger and have fresh legs."