The Reds skipper has not appeared at the Theatre of Dreams since last November, when he featured in the 1-1 draw with Newcastle United, and he is desperate to make up for lost time by helping to regain the league title.
"I've been waiting for it for a long time," he told United Review. "I've already played at Everton, but I'm looking forward to playing at Old Trafford.
"It's always nice to run out in front of 76,000 people at home. We have had great support through the years; we know from the first minute we will have really strong support, and we will need that. We know it will be a difficult game and it's important to win and have three points, then we can start from there."