Ferguson did admit the search for Scholes' replacement would go on, though, even if getting the right man will prove difficult.
"It is a loss. He was a player of a lifetime. In his 20 years at the club, it is hard to pick out a bad game," said the Scot.
"He was such a great, consistent player for us. I don't think we will find another Paul Scholes.
"But hopefully we can replace him. Maybe we will find a different type of player. Manchester United do that.
"Time and time again we have faced this problem. We have lost great players and you are worrying about it.
"But eventually something turns up, either through our youth system or we will identify someone.
"Obviously, there is a bit of work being done on that at the moment by our scouting department.
"But also we are analysing the capabilities of the young players from our youth team. We will give them that opportunity."