Fowler believes the high-flying Reds face a tough task to keep up their form, with the influential pair out until the new year.
He told the Daily Star Sunday: "It will be tough. Steven, in particular, is a big miss. Everything good Liverpool do comes through him and Suarez.
"Daniel maybe needs a break because he missed a lot of pre-season.
"He was scoring but his form started to dip a little bit. He was playing catch-up and getting little niggles but he'll be back to how he was.
"Brendan must tell them this is a chance for them to show people Liverpool are not a two-man team."