The Galaxy were served by Juninhoâ€™s superb 58th minute goal to take 1-0 win with them back to Los Angeles.
A massive crowd of just over 36,000 turned up to Qwest Field to see their team in action but the Sounders drew a blank despite having a solid strike force with the likes of Fredy Montero, Oâ€™Brian White, Steve Zakuani and Alvaro Fernandez all in attacking positions and producing six shots on goal to two.
But it was Bruce Arenaâ€™s men who struck the one and only goal in the game when Brazilian midfielder Juninho received a pass from left-back Todd Dunivant and proceeded to hammer home from long range, sending a sprawling Kasey Keller to his right and the veteran could only slightly get a glove on the swerving shot.
Sounders coach Sigi Schmid admitted that the Galaxy, who have now beaten Seattle in their past five MLS meetings, are clearly a team they struggle to beat.
"Sometimes you have a bogey team, a team that for some reason, it just doesnâ€™t work for you and, right now, theyâ€™re that team for us,â€ť Schmid said.
â€śThereâ€™s a lot of games between now and July and weâ€™ve got to focus on those other games. Our guys are pissed, our guys are disappointed â€“ especially since itâ€™s the opening game of the season and we havenâ€™t lost an opener before.â€ť
The Sounders will now prepare for their trip to New York to take on the Red Bulls on Saturday whilst the Galaxy host New England Revolution on Monday.