The Bianconeri are the only side still unbeaten and must get a win to stay clear at the top of the table, though they are resisting talk of the Scudetto.
"This can be an important stepping stone towards something very prestigious," said Pirlo.
"Francesco Totti is going through a difficult moment because of injuries, but he remains a great champion. I often talk to Daniele De Rossi when we're on international duty. His contract with Roma expires in June, but it's up to him to decide whether or not to change clubs."